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SLP-76(Phospho-Ser376) Rabbit Polyclonal Antibody, 50ul Electronic Pipette The encoded protein functions as

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SLP-76(Phospho-Ser376) Rabbit Polyclonal Antibody, 50ul Electronic Pipette The encoded protein functions asSLP 76 was originally identified as a substrate of the ZAP 70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP 76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2 terminus contains an acidic

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Description

The encoded protein functions as an adaptor protein that complexes with Cullin 3 and other proteins to form the Cullin 3-based E3 ubiquitin-protein ligase complex

the chromatin licensing and DNA replication factor 1

10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members

Platelet glycoprotein Ib (GPIb) is a heterodimeric transmembrane protein consisting of a disulfide-linked 140 kD alpha chain and 22 kD beta chain

SLP-76(Phospho-Ser376) Rabbit Polyclonal Antibody, 50ul Electronic Pipette The encoded protein functions asSLP 76 was originally identified as a substrate of the ZAP 70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP 76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2 terminus contains an acidic

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