Ksr2 Polyclonal Antibody, 100ul Cell Proliferation Expression of the protein has

Expression of the protein has been observed in various human cancer cell lines established from malignant tumors

The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction

formerly thought to be a beta chain

and in the paracellular barrier to prevent sodium back-leakage in distal colon

Ksr2 Polyclonal Antibody, 100ul Cell Proliferation Expression of the protein hasLocation regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8 mediated signaling. Acts as a negative regulator of MAP3K3 mediated activation of ERK, JNK and NF kappa B pathways, inhibiting MAP3K3 mediated interleukin 8 production.