Rb Polyclonal Antibody, 50ul[BT-AP07685] Peptide Library This gene is one of

This gene is one of the contiguous genes at 7q11

this protein lacks the platelet-binding site

This gene encodes a receptor for ephrin-B family members

It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins

Rb Polyclonal Antibody, 50ul[BT-AP07685] Peptide Library This gene is one ofRB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.