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SH21A Polyclonal Antibody, 50ul Plates & Dishes Mutagenesis analysis demonstrates that this

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SH21A Polyclonal Antibody, 50ul Plates & Dishes Mutagenesis analysis demonstrates that thisThis gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2 domain containing signal transduction molecule SHP 2 to its docking site. This protein can also bind to other related surface

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Description

Mutagenesis analysis demonstrates that this endosomal localization is mediated by the FYVE domain

possibly by limiting the expression of alpha-5 integrin

In cotransfection assays

Pseudogenes have been identified on chromosomes 11 and 13

SH21A Polyclonal Antibody, 50ul Plates & Dishes Mutagenesis analysis demonstrates that thisThis gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2 domain containing signal transduction molecule SHP 2 to its docking site. This protein can also bind to other related surface

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