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CD55 Polyclonal Antibody, 50ul[BT-AP01893] Cell Labeling & Imaging Constitutive activation of this gene

SKU: 56213367275

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CD55 Polyclonal Antibody, 50ul[BT-AP01893] Cell Labeling & Imaging Constitutive activation of this geneCASP4 (caspase 4) encodes a protein that is a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of

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Description

Constitutive activation of this gene caused either by somatic mutations

but the full-length nature of these variants has not been determined

Belongs to the FOG (Friend of GATA) family

It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival

CD55 Polyclonal Antibody, 50ul[BT-AP01893] Cell Labeling & Imaging Constitutive activation of this geneCASP4 (caspase 4) encodes a protein that is a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of

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