PDX-1 Polyclonal Antibody, 100ul Sample Library Tubes Members of this family encode
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PDX-1 Polyclonal Antibody, 100ul Sample Library Tubes Members of this family encodeThe protein encoded by PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early onset insulin dependent
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