Rat Focal Adhesion Kinase 1, PTK2 ELISA Kit, 96T Recombinant Protein Expression This gene may be associated

This gene may be associated with many disease states

inflammatory cell apoptosis

Released HMGB1:nucleosome complexes formed during apoptosis can signal through TLR2 to induce cytokine production

Involved in TNF-alpha-induced NF-kappa-B transcriptional repression by inducing endoprotease processing of the transcription factor NF-kappa-B p65/RELA subunit (PubMed: 18212740)

Rat Focal Adhesion Kinase 1, PTK2 ELISA Kit, 96T Recombinant Protein Expression This gene may be associatedNon receptor protein tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart