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CD59 Polyclonal Antibody, 50ul[BT-AP01671] Micro Centrifuge Tubes Defects in this gene can

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CD59 Polyclonal Antibody, 50ul[BT-AP01671] Micro Centrifuge Tubes Defects in this gene canCentromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3 H4)2 tetrameric core of the

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Description

Defects in this gene can also cause cone-rod dystrophy type 11| a disease characterized by the initial degeneration of cone photoreceptor cells and resulting in loss of color vision and visual acuity| followed by the degeneration of rod photoreceptor cells| which progresses to night blindness and the loss of peripheral vision

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Multiple alternatively spliced transcripts have been observed

Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them

CD59 Polyclonal Antibody, 50ul[BT-AP01671] Micro Centrifuge Tubes Defects in this gene canCentromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3 H4)2 tetrameric core of the

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