Tuberin/TSC2(Phospho-Ser1254) Rabbit Polyclonal Antibody, 50ul Serum including mouse Mekk2

including mouse Mekk2

with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions

The N-terminus is poorly conserved and may impart additional roles in developmental regulation

Expression of this gene is highly restricted

Tuberin/TSC2(Phospho-Ser1254) Rabbit Polyclonal Antibody, 50ul Serum including mouse Mekk2Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.