FoxO3A Polyclonal Antibody, 50ul[BT-AP03333] Human Genome Knockout Libraries The encoded protein contains three

The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding

which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane

which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids

which contributes to Alzheimer's disease

FoxO3A Polyclonal Antibody, 50ul[BT-AP03333] Human Genome Knockout Libraries The encoded protein contains threeFOXO3 belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. FOXO3 likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.