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CD58 Polyclonal Antibody, 50ul[BT-AP01713] Bottle-Top Dispenser Platelet glycoprotein Ib (GPIb) is

SKU: 57419509709

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CD58 Polyclonal Antibody, 50ul[BT-AP01713] Bottle-Top Dispenser Platelet glycoprotein Ib (GPIb) isCERKL was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. CERKL encodes a protein (ceramide kinase like) with ceramide kinase like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa

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Description

Platelet glycoprotein Ib (GPIb) is a heterodimeric transmembrane protein consisting of a disulfide-linked 140 kD alpha chain and 22 kD beta chain

PSCA includes a polymorphism that results in an upstream start codon in some individuals

These filters have a MWCO of 30 kDa

The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs)

CD58 Polyclonal Antibody, 50ul[BT-AP01713] Bottle-Top Dispenser Platelet glycoprotein Ib (GPIb) isCERKL was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. CERKL encodes a protein (ceramide kinase like) with ceramide kinase like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa

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