Raf-1(Phospho Ser43) Polyclonal Antibody, 100ul Stepper including genetic engineering

including genetic engineering

This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain

The hes related family bHLH transcription factor with YRPW motif 2 forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription

but decreased response to IL28B

Raf-1(Phospho Ser43) Polyclonal Antibody, 100ul Stepper including genetic engineeringThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.