Phospho-AIP4 (Y420) Polyclonal Antibody, 100ul Antibody Development LY6G5C belongs to a cluster

LY6G5C belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6

1 - 100mL)

which is often found in patients with chronic myelogenous leukemia

Mutations in this gene have been associated with autosomal recessive dilated cardiomyopathy

Phospho-AIP4 (Y420) Polyclonal Antibody, 100ul Antibody Development LY6G5C belongs to a clusterITCH (itchy E3 ubiquitin protein ligase) encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations