ERF(Phospho Thr526) Polyclonal Antibody, 100ul Bacterial Expression Malfunction or loss of p53

Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome

Bone morphogenetic protein 8A may play a role in development of the reproductive system

Symptoms associated with mutations in this gene

This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis

ERF(Phospho Thr526) Polyclonal Antibody, 100ul Bacterial Expression Malfunction or loss of p53ETS2 is a transcription factor and protooncogene involved in development, apoptosis, and the regulation of telomerase. The protein encoded by this gene binds to the ETS2 promoter and is a strong repressor of ETS2 transcription. Several transcript variants encoding two different isoforms have been found for this gene.