HES4 Polyclonal Antibody, 100ul Live Cell Imaging GDF5 encodes a secreted ligand

GDF5 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins

Studies of the mouse counterpart suggest that this gene may function as a testis specific transcription factor during spermatogenesis

The protein encoded by this gene is similar to the gene product of S14| a rat gene whose expression is limited to liver and adipose tissue and is controlled by nutritional and hormonal factors

Contains 5 C2 domains

HES4 Polyclonal Antibody, 100ul Live Cell Imaging GDF5 encodes a secreted ligandHas a particular type of basic domain (presence of a helix interrupting proline) that binds to the N box (CACNAG), rather than the canonical E box (CANNTG).,The C terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy related proteins.,Transcriptional repressor. Binds DNA on N box motifs: 5' CACNAG 3'.,Contains 1