PUS10 Rabbit Polyclonal Antibody, 50ul Stepper most of which utilize a

most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow

This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation

is a 482 amino acid protein that localizes to the lysosomal membrane and belongs to the CCZ1 family

a subnuclear structure

PUS10 Rabbit Polyclonal Antibody, 50ul Stepper most of which utilize aPseudouridination the isomerization of uridine to pseudouridine is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases such as PUS10 catalyze pseudouridination of structural RNAs including transfer ribosomal and splicing RNAs. These enzymes also act as RNA chaperones facilitating the correct folding and assembly of tRNAs (McCleverty