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TCAL8 Polyclonal Antibody, 20ul Custom DNA Oligos INTS2 (integrator complex subunit 2)

SKU: 59853085382

4.1
EUR111.00 EUR148.00

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TCAL8 Polyclonal Antibody, 20ul Custom DNA Oligos INTS2 (integrator complex subunit 2)This gene encodes a member of the transcription elongation factor A (SII) like (TCEAL) gene family. Members of this family contain TFA domains and may function as nuclear phosphoproteins that modulate transcription in a promoter context dependent manner. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform.

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Description

INTS2 (integrator complex subunit 2) is a subunit of the Integrator complex

the complex is then transported across the cell to be secreted at the apical surface

Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I

Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS)

TCAL8 Polyclonal Antibody, 20ul Custom DNA Oligos INTS2 (integrator complex subunit 2)This gene encodes a member of the transcription elongation factor A (SII) like (TCEAL) gene family. Members of this family contain TFA domains and may function as nuclear phosphoproteins that modulate transcription in a promoter context dependent manner. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform.

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