RM38 Polyclonal Antibody, 100ul Gene Synthesis Cullin 3 plays a critical

Cullin 3 plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex

Alternative splicing results in multiple transcript variants that encode different protein isoforms

and is partly homologous to the cell division cycle protein CDC48

This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein| Drosha

RM38 Polyclonal Antibody, 100ul Gene Synthesis Cullin 3 plays a criticalMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S