SPIT2 Polyclonal Antibody, 50ul Immunology DNA ligase 4 encoded by

DNA ligase 4 encoded by LIG4 is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction

manganese or divalent iron ions

axon outgrowth and guidance

PubMed: 19208651)

SPIT2 Polyclonal Antibody, 50ul Immunology DNA ligase 4 encoded byThis gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.