GTSE1 Polyclonal Antibody, 20ul sgRNA Oligos Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants encoding different isoforms have been found for BARD1

This protein contains 7 leucine-rich repeats and 12 immunoglobulin-like C2-type domains related to perlecan

laminin receptor 1

and FBXW8 proteins

GTSE1 Polyclonal Antibody, 20ul sgRNA Oligos Multiple alternatively spliced transcript variantsThe protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.