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HECW1 Polyclonal Antibody, 50ul Antibodies TBL2 is deleted in Williams-Beuren

SKU: 61289660445

4.9
PLN162.00 PLN211.00

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HECW1 Polyclonal Antibody, 50ul Antibodies TBL2 is deleted in Williams-BeurenE3 ubiquitin protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway: Protein modification; protein ubiquitination.,Contains 1 C2 domain.,Contains 1 HECT (E6AP type E3 ubiquitin protein ligase) domain.,Contains 2 WW

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Description

TBL2 is deleted in Williams-Beuren syndrome

Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism

that dimerize to form the active enzyme

PTM:N- and O-glycosylated

HECW1 Polyclonal Antibody, 50ul Antibodies TBL2 is deleted in Williams-BeurenE3 ubiquitin protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway: Protein modification; protein ubiquitination.,Contains 1 C2 domain.,Contains 1 HECT (E6AP type E3 ubiquitin protein ligase) domain.,Contains 2 WW

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