Mnk1 Polyclonal Antibody, 100ul[BT-AP05495] Micro Centrifuge Tubes The encoded protein tightly associates

The encoded protein tightly associates with cyclin-dependent kinase 9

Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation

and dysequilibrium syndrome 3 (CMARQ3)

A mutation in this gene has been correlated with T-cell immunodeficiency

Mnk1 Polyclonal Antibody, 100ul[BT-AP05495] Micro Centrifuge Tubes The encoded protein tightly associatesMKNK1 (MAP kinase interacting serine threonine kinase 1) encodes a Ser Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C terminal region of eIF4G. Alternatively spliced transcript variants have been noted for MKNK1.