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GPR19 Polyclonal Antibody, 100ul 3D Culture Mutations in this gene are

SKU: 62194946837

4.1
PLN123.75 PLN170.75

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GPR19 Polyclonal Antibody, 100ul 3D Culture Mutations in this gene areGPR19 is a gene on chromosome 12p13. 1 that encodes an orphan G protein coupled receptor. G Protein Coupled Receptor 19 is a orphan receptor. Among its related pathways are Peptide ligand binding receptors. Gene Ontology (GO) annotations related to this gene include G protein coupled receptor activity. An important paralog of this gene is AVPR1B.

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Description

Mutations in this gene are associated with two types of recessive osteochondrodysplasia| Dyggve-Melchior-Clausen (DMC) dysplasia and Smith-McCort (SMC) dysplasia| which involve both skeletal defects and mental retardation

It is able to form homodimers and heterodimers with other family members| which include Mad| Mxi1 and Myc

Represses the transcriptional activator activity of BRCA1 (PubMed: 20160719)

and alterations in the expression of PAX5 are thought to contribute to neoplastic transformation

GPR19 Polyclonal Antibody, 100ul 3D Culture Mutations in this gene areGPR19 is a gene on chromosome 12p13. 1 that encodes an orphan G protein coupled receptor. G Protein Coupled Receptor 19 is a orphan receptor. Among its related pathways are Peptide ligand binding receptors. Gene Ontology (GO) annotations related to this gene include G protein coupled receptor activity. An important paralog of this gene is AVPR1B.

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