RHG24 Polyclonal Antibody, 20ul Buffers & Solutions It encodes a protein which

It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat

GO annotations related to this gene include calcium ion binding and thiol-dependent ubiquitin-specific protease activity

and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease

late infantile

RHG24 Polyclonal Antibody, 20ul Buffers & Solutions It encodes a protein whichThis gene encodes a Rho GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants.