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HSP27 Polyclonal Antibody, 100ul[BT-AP10198] Multiplex Immunoassays The encoded protein binds RNA

SKU: 64286485500

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HSP27 Polyclonal Antibody, 100ul[BT-AP10198] Multiplex Immunoassays The encoded protein binds RNAThe protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot Marie Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).

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Description

The encoded protein binds RNA and interacts with two other EJC core components

Eukaryotic translation initiation factor 2 alpha kinase 3 encoded by EIF2AK3 phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2

indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis

Methylation of the promoter of CEBPZ or mutations within CEBPZ may be correlated with occurance of acute myeloid leukemia (AML)

HSP27 Polyclonal Antibody, 100ul[BT-AP10198] Multiplex Immunoassays The encoded protein binds RNAThe protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot Marie Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).

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