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MITF(Phospho Ser180) Polyclonal Antibody, 50ul Bacterial Expression This protein is thought to

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MITF(Phospho Ser180) Polyclonal Antibody, 50ul Bacterial Expression This protein is thought toThis gene encodes a transcription factor that contains both basic helix loop helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome.

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Description

This protein is thought to be a negative regulator of AP-1/ATF transcriptional events

breast and hepatocellular cancers and Wilms' tumor

The encoded protein is a subunit of an integral sperm membrane glycoprotein called fertilin

which have been implicated in the regulation of NK cell function

MITF(Phospho Ser180) Polyclonal Antibody, 50ul Bacterial Expression This protein is thought toThis gene encodes a transcription factor that contains both basic helix loop helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome.

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