IGF2-BP2 Polyclonal Antibody, 50ul Culture Plate Inserts The encoded protein KCNJ3

The encoded protein KCNJ3

The small size of the his-tag

The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport

Mutations in KRT8 cause cryptogenic cirrhosis

IGF2-BP2 Polyclonal Antibody, 50ul Culture Plate Inserts The encoded protein KCNJ3IGF2BP2 encodes a member of the IGF II mRNA binding protein (IMP) family. The insulin like growth factor 2 mRNA binding protein 2 encoded by this gene contains four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternative promoter usage and alternate splicing result in multiple variants encoding different isoforms.