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Ku-70 Polyclonal Antibody, 20ul[BT-AP04891] RNA Synthesis Expression of this protein is

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Ku-70 Polyclonal Antibody, 20ul[BT-AP04891] RNA Synthesis Expression of this protein isThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2

Male mice with mutations in the mouse ortholog of this gene are sterile and spermatocytes display an early meiotic arrest phenotype

and binds copper

AFP encodes alpha-fetoprotein

Ku-70 Polyclonal Antibody, 20ul[BT-AP04891] RNA Synthesis Expression of this protein isThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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