NEDD4L Rabbit Polyclonal Antibody, 100ul Monoclonal Antibody Preparation BAD and BAX

BAD and BAX

Genetic variation at this locus has been associated with a range of behavioral phenotypes

Unlike other proteins of the group| which cycle in the early secretory pathway and are predominantly associated with post endoplasmic reticulum membranes| the protein encoded by this gene is a non-cycling resident protein of the ER| where it functions as a cargo receptor for glycoproteins

are characterized by an approximately 40-amino acid F-box motif

NEDD4L Rabbit Polyclonal Antibody, 100ul Monoclonal Antibody Preparation BAD and BAXThis gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin conjugating enzymes to protein substrates thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial