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CEP55(Phospho Ser425) Polyclonal Antibody, 100ul Microplate Mixer The product of this gene

SKU: 65523745532

4.4
USD141.00 USD187.00

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CEP55(Phospho Ser425) Polyclonal Antibody, 100ul Microplate Mixer The product of this genePlays a role in mitotic exit and cytokinesis. Not required for microtubule nucleation. Recruits PDCD6IP and TSG101 to midbody during cytokinesis.,PTM: There is a hierachy of phosphorylation, where both Ser 425 and Ser 428 are phosphorylated at the onset of mitosis, prior to Ser 436. Phosphorylation at Ser 425 and Ser 428 is required for dissociation from the centrosome at the G2 M boundary. Phosphorylation at the 3 sites, Ser 425, Ser 428 and Ser 436,

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Description

The product of this gene belongs to the Serine/Threonine protein kinase family| and to the Ca(2+)/calmodulin-dependent protein kinase subfamily

WNK1 encodes a member of the WNK subfamily of serine/threonine protein kinases

Acts as a regulator of PCK1 expression and gluconeogenesis by a mechanism that involves

Mutations and loss of expression of netrin suggest that variation in netrin may be involved in cancer development

CEP55(Phospho Ser425) Polyclonal Antibody, 100ul Microplate Mixer The product of this genePlays a role in mitotic exit and cytokinesis. Not required for microtubule nucleation. Recruits PDCD6IP and TSG101 to midbody during cytokinesis.,PTM: There is a hierachy of phosphorylation, where both Ser 425 and Ser 428 are phosphorylated at the onset of mitosis, prior to Ser 436. Phosphorylation at Ser 425 and Ser 428 is required for dissociation from the centrosome at the G2 M boundary. Phosphorylation at the 3 sites, Ser 425, Ser 428 and Ser 436,

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