Human Hypoxia-inducible Factor 1Α, HIF-1A ELISA Kit , 96T Antibody Humanization Introducing CellSafeââ€

Introducing CellSafeââ€

The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain

It encodes Disintegrin and metalloproteinase domain-containing protein 10 with similarity to collagens X and VIII and complement factor C1q

MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or regulate its function

Human Hypoxia-inducible Factor 1Α, HIF-1A ELISA Kit , 96T Antibody Humanization Introducing CellSafeââ€Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis