Topo II Alpha Polyclonal Antibody, 50ul[BT-AP09133] Immunology The encoded protein is localized

The encoded protein is localized to the cytosol and mitochondria| and associates with membranes through an isoprenyl modification near the C-terminus

its expression in lymphoid follicles is restricted to the cells of germinal centre

liver fibrosis and polydactyly

which is characterized by severe lung complications and liver dysfunction

Topo II Alpha Polyclonal Antibody, 50ul[BT-AP09133] Immunology The encoded protein is localizedTOP2A encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering