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S7A14 Rabbit Polyclonal Antibody, 100ul PCR Series CYP2D6 can vary in copy

SKU: 66401930222

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S7A14 Rabbit Polyclonal Antibody, 100ul PCR Series CYP2D6 can vary in copyThis gene is predicted to encode a glycosylated cationic amino acid transporter protein with 14 transmembrane domains. This gene is primarily expressed in skin fibroblasts neural tissue and primary endothelial cells and its protein is predicted to mediate lysosomal uptake of cationic amino acids. Mutations in this gene are associated with autosomal recessive retinitis pigmentosa. In mice this gene is expressed in the photoreceptor layer of the retina

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Description

CYP2D6 can vary in copy number and individuals with the ultrarapid metabolizer phenotype can have 3 or more active copies of the gene

An important paralog of this gene is RASL10A

Has a role in myogenic differentiation and in remodeling processes of adult muscles that occur in response to physiological stimuli

This secreted protease (matrix metallopeptidase 10) breaks down fibronectin

S7A14 Rabbit Polyclonal Antibody, 100ul PCR Series CYP2D6 can vary in copyThis gene is predicted to encode a glycosylated cationic amino acid transporter protein with 14 transmembrane domains. This gene is primarily expressed in skin fibroblasts neural tissue and primary endothelial cells and its protein is predicted to mediate lysosomal uptake of cationic amino acids. Mutations in this gene are associated with autosomal recessive retinitis pigmentosa. In mice this gene is expressed in the photoreceptor layer of the retina

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