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NR0B2 Polyclonal Antibody, 50ul Variant Libraries An important paralog of PGRMC2

SKU: 66623669390

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NR0B2 Polyclonal Antibody, 50ul Variant Libraries An important paralog of PGRMC2The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand binding domain but lacks a conventional DNA binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid

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Description

An important paralog of PGRMC2 is PGRMC1

Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10)

The concentrative nucleoside transporter (CNT) family comprises three members: CNT1

The protein encoded by this gene is the receptor for colony stimulating factor 1| a cytokine which controls the production| differentiation| and function of macrophages

NR0B2 Polyclonal Antibody, 50ul Variant Libraries An important paralog of PGRMC2The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand binding domain but lacks a conventional DNA binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid

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