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ASPP1 Polyclonal Antibody, 20ul Peptide Synthesis Heterozygous mutations in the this

SKU: 67058825552

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ASPP1 Polyclonal Antibody, 20ul Peptide Synthesis Heterozygous mutations in the thisThis gene encodes a member of the ASPP (apoptosis stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein protein interactions. ASPP proteins are required for the induction of apoptosis by p53 family proteins. They promote DNA binding and transactivation of p53 family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F

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Description

Heterozygous mutations in the this gene cause auditory-pigmentary syndromes

May be concerned with increased secretion of cytokines associated with cellular senescence

and interleukin 1 receptor

It binds mutliple lipid-containing molecules| including phosphatidylserine| phosphatidylinositol 4-phosphate (PI4P) and oxysterol| and promotes their exchange between the endoplasmic reticulum and the plasma membrane

ASPP1 Polyclonal Antibody, 20ul Peptide Synthesis Heterozygous mutations in the thisThis gene encodes a member of the ASPP (apoptosis stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein protein interactions. ASPP proteins are required for the induction of apoptosis by p53 family proteins. They promote DNA binding and transactivation of p53 family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F

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