ET-1 Polyclonal Antibody, 20ul Peptide Library The presence of polymorphisms in
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ET-1 Polyclonal Antibody, 20ul Peptide Library The presence of polymorphisms inEDN1 encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.
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