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ET-1 Polyclonal Antibody, 20ul Peptide Library The presence of polymorphisms in

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ET-1 Polyclonal Antibody, 20ul Peptide Library The presence of polymorphisms inEDN1 encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

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Description

The presence of polymorphisms in the N-terminal arginine-rich region

Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ)

3- and alpha-2

during the differentiation of heart

ET-1 Polyclonal Antibody, 20ul Peptide Library The presence of polymorphisms inEDN1 encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

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