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Flt3 Polyclonal Antibody, 20ul[BT-AP03283] sgRNA Library Construction Mutations in this gene are

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Flt3 Polyclonal Antibody, 20ul[BT-AP03283] sgRNA Library Construction Mutations in this gene areFLT3 encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis,

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Description

Mutations in this gene are associated with Ehlers-Danlos syndrome

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which is present only in muscle tissues

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Flt3 Polyclonal Antibody, 20ul[BT-AP03283] sgRNA Library Construction Mutations in this gene areFLT3 encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis,

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