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Phospho-BLM (T99) Polyclonal Antibody, 20ul Gloves This kinase contains 2 nonidentical

SKU: 69852530974

4.8
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Phospho-BLM (T99) Polyclonal Antibody, 20ul Gloves This kinase contains 2 nonidenticalThe Bloom syndrome gene product is related to the RecQ subset of DExH box containing DNA helicases and has both DNA stimulated ATPase and ATP dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3' 5' helicase activity. The normal protein may act to suppress inappropriate recombination.

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Description

This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates

poly(ADP-ribose) polymerase 1 may be the site of mutation in Fanconi anemia

LTE4 and 12-HETE

With a precise 0

Phospho-BLM (T99) Polyclonal Antibody, 20ul Gloves This kinase contains 2 nonidenticalThe Bloom syndrome gene product is related to the RecQ subset of DExH box containing DNA helicases and has both DNA stimulated ATPase and ATP dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3' 5' helicase activity. The normal protein may act to suppress inappropriate recombination.

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