DAB2 Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification They are differentially regulated after

They are differentially regulated after early development

A pseudogene of this gene is located on the long arm of chromosome 7

Alström syndrome

hypomethylation of the CAGE promoter region is associated with tumor progression and may serve as a valuable marker in cancer diagnosis

DAB2 Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification They are differentially regulated afterThis gene encodes a mitogen responsive phosphoprotein. It is expressed in normal ovarian epithelial cells but is down regulated or absent from ovarian carcinoma cell lines suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2 an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras) via its C terminal proline rich sequences and may thus modulate growth factor Ras