PAR10 Polyclonal Antibody, 50ul Petri Dishes Inhibits the degradation of target

Inhibits the degradation of target proteins by the proteasome (PubMed: 12084015)

The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway

Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas| some of which may result in the formation of fusion proteins

Mutations in ABCB7 have been associated with mitochondrial iron accumulation and isodicentric (X) (q13) and sideroblastic anemia

PAR10 Polyclonal Antibody, 50ul Petri Dishes Inhibits the degradation of targetPoly(ADP ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP ribose to histones. PARPs can also function as transcriptional cofactors (Yu et al., 2005