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PTEN(Phospho Ser370) Polyclonal Antibody, 100ul Serological Pipets The N-terminal domain of this

SKU: 70603960636

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PTEN(Phospho Ser370) Polyclonal Antibody, 100ul Serological Pipets The N-terminal domain of thisThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide

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Description

The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex

Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses

This gene encodes the DUOX1 activator or maturation factor DUOXA1

MIM 300172)

PTEN(Phospho Ser370) Polyclonal Antibody, 100ul Serological Pipets The N-terminal domain of thisThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide

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