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Bcl-7a Polyclonal Antibody, 100ul Hybridoma Antibody Sequencing Alternatively spliced transcript variants encoding

SKU: 70947902105

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Bcl-7a Polyclonal Antibody, 100ul Hybridoma Antibody Sequencing Alternatively spliced transcript variants encodingBCL7A (BCL tumor suppressor 7A) is directly involved, with Myc and IgH, in a three way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high grade B cell non Hodgkin lymphoma. The N terminal segment involved in the translocation includes the region that shares a strong sequence similarity

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Description

Alternatively spliced transcript variants encoding the same protein have been observed

Several alternatively spliced transcript variants encoding the same protein have been observed for this gene

It contains a single doublecortin domain and is unable to bind microtubules and to regulate microtubule polymerization

Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis

Bcl-7a Polyclonal Antibody, 100ul Hybridoma Antibody Sequencing Alternatively spliced transcript variants encodingBCL7A (BCL tumor suppressor 7A) is directly involved, with Myc and IgH, in a three way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high grade B cell non Hodgkin lymphoma. The N terminal segment involved in the translocation includes the region that shares a strong sequence similarity

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