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INGR2 Polyclonal Antibody, 20ul Inoculating Loops/Needles It interacts with another ubiquitin

SKU: 71327229207

4.5
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INGR2 Polyclonal Antibody, 20ul Inoculating Loops/Needles It interacts with another ubiquitinThis gene (IFNGR2) encodes the non ligand binding beta chain of the gamma interferon receptor. Human interferon gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X linked inheritance.

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Description

It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system

|PTM:Phosphorylated in the C-terminal upon stimulation by nerve growth factor (NGF) and epidermal growth factor (EGF)

|tissue specificity:Detected in spleen and thyroid| and at lower levels in kidney| brain| lung and pancreas

encodes over 1

INGR2 Polyclonal Antibody, 20ul Inoculating Loops/Needles It interacts with another ubiquitinThis gene (IFNGR2) encodes the non ligand binding beta chain of the gamma interferon receptor. Human interferon gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X linked inheritance.

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