PDK1 Polyclonal Antibody, 50ul[BT-AP07028] Electronic Pipette Alternative splicing results in four

Alternative splicing results in four transcript variants encoding four distinct isoforms

Allelic variants of this gene have been associated with obesity

An important paralog of this gene is RABEP2

This protein was demonstrated to interact with and inhibit the activities of both C alpha and C beta catalytic subunits of the PKA

PDK1 Polyclonal Antibody, 50ul[BT-AP07028] Electronic Pipette Alternative splicing results in fourPyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced