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CD55 Polyclonal Antibody, 100ul[BT-AP02376] Molecular Biology A polymorphism in NPY resulting

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CD55 Polyclonal Antibody, 100ul[BT-AP02376] Molecular Biology A polymorphism in NPY resultingCYP11B1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11 beta

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Description

A polymorphism in NPY resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels

Can mediate aggregation most likely through a homophilic molecular interaction

and is thought to function in a signaling pathway essential for vascular developent

Overexpression of this gene may play a role in leukemogenesis| and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein

CD55 Polyclonal Antibody, 100ul[BT-AP02376] Molecular Biology A polymorphism in NPY resultingCYP11B1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11 beta

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