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Mutations in this gene cause nephronophthisis (NPHP)| an autosomal recessive kidney disease characterized by tubular basement membrane disruption| interstitial lymphohistiocytic cell infiltration| and development of cysts at the corticomedullary border of the kidneys

are integral transmembrane proteins that exchange extracellular Na+ for intracellular H+

Mitotic and Regulation of PLK1 Activity at G2/M Transition

SRGP2 Rabbit Polyclonal Antibody, 20ul Dry Bath Unleash your risk-taking nature withThis locus encodes a member of the SLIT ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1 and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species the paralogs are found only in the genus Homo and not in the genomes of non human great apes. Alternatively spliced