PRAK Polyclonal Antibody, 20ul[BT-AP07383] In vitro Assessment membrane-bound isoform encoded by NRG1

membrane-bound isoform encoded by NRG1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems

They form a three-tiered signaling module composed of MAPKKKs

The encoded protease (cathepsin G) has a specificity similar to that of chymotrypsin C

The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids

PRAK Polyclonal Antibody, 20ul[BT-AP07383] In vitro Assessment membrane-bound isoform encoded by NRG1The protein encoded by MAPKAPK5 (mitogen activated protein kinase activated protein kinase 5) is a tumor suppressor and member of the serine threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1 ERK, MAPK14 p38 alpha, and MAPK11 p38 beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation