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HBG1 Rabbit Polyclonal Antibody, 20ul Reagent Reservoirs KCNA1 encodes a voltage-gated delayed

SKU: 72494829768

4.5
SEK97.20 SEK141.20

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HBG1 Rabbit Polyclonal Antibody, 20ul Reagent Reservoirs KCNA1 encodes a voltage-gated delayedThe gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta thalassemias and related conditions gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G gamma product (HBG2)

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Description

KCNA1 encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel

ARNT2 (aryl hydrocarbon receptor nuclear translocator 2) encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors

This gene was found to be a p53-regulated DNA damage-inducible gene

This locus represents a polymorphic pseudogene| where some individuals contain an allele that can encode a full-length protein| while others have a non-functional allele containing a premature stop codon (reference SNP rs237520) that truncates the coding sequence

HBG1 Rabbit Polyclonal Antibody, 20ul Reagent Reservoirs KCNA1 encodes a voltage-gated delayedThe gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta thalassemias and related conditions gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G gamma product (HBG2)

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