CLSPN Polyclonal Antibody, 50ul Gene Synthesis It is thought to function

It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes

This gene was initially mapped to chromosome 14

A second breast cancer susceptibility gene

Working temperature range: -80°C – 121°C

CLSPN Polyclonal Antibody, 50ul Gene Synthesis It is thought to functionThe product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a normal S phase. Multiple transcript variants encoding different isoforms have been found for this gene.