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COA1 Rabbit Polyclonal Antibody, 50ul Enzymes Protects cells from CD95-mediated apoptosis

SKU: 72689448697

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SEK162.00 SEK200.00

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COA1 Rabbit Polyclonal Antibody, 50ul Enzymes Protects cells from CD95-mediated apoptosis

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Description

Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells

Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified

The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers

The authors of a publication on the effects of siRNA-mediated sacsin knockdown concluded that sacsin protects against mutant ataxin-1 and suggest that "the large multi-domain sacsin protein is able to recruit Hsp70 chaperone action and has the potential to regulate the effects of other ataxia proteins" (Parfitt et al

COA1 Rabbit Polyclonal Antibody, 50ul Enzymes Protects cells from CD95-mediated apoptosis

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